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BQ-123

SKU: orb2692773

Description

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

Images & Validation

Key Properties

TargetEndothelin Receptor
Molecular Weight610.7
Protein SequenceCyclo(d-DP-d-VL-d-W)
Purity≥95%

Storage & Handling

Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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BQ-123 (orb2692773)

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