Boc-Val-Cit-PAB-PNP

SKU: orb1219590

Description

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Research Area

Signal Transduction

Key Properties

• CAS Number: 870487-10-8
• MW: 644.67
• Purity: >98% (HPLC)
• Formula: C₃₀H₄₀N₆O₁₀
• SMILES: CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1
• Target: PROTAC
• Solubility: In Vitro: DMSO : 100 mg/mL (155.12 mM)

Bioactivity

• In Vitro:
  ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTAC