Boc-11-aminoundecanoic acid

SKU: orb1940675

Description

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432.(In Vitro):MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Images & Validation

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Key Properties

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CAS Number	10436-25-6
MW	301.427
Purity	>98% (HPLC)
Formula	C₁₆H₃₁NO₄
SMILES	CC(C)(C)OC(=O)NCCCCCCCCCCC(O)=O
Target	Fungal\| Human Endogenous Metabolite

Bioactivity

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In Vitro	MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Fungal| Human Endogenous Metabolite

Protocol Information

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