Boc-11-aminoundecanoic acid

SKU: orb1940675

Description

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432.(In Vitro):MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Key Properties

• CAS Number: 10436-25-6
• MW: 301.427
• Purity: >98% (HPLC)
• Formula: C₁₆H₃₁NO₄
• SMILES: CC(C)(C)OC(=O)NCCCCCCCCCCC(O)=O
• Target: Fungal| Human Endogenous Metabolite

Bioactivity

• In Vitro:
  MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Fungal| Human Endogenous Metabolite