BMY 7378 dihydrochloride

SKU: orb1222517

Description

BMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.

Key Properties

• CAS Number: 21102-95-4
• MW: 458.42
• Purity: >98% (HPLC)
• Formula: C₂₂H₃₃Cl₂N₃O₃
• SMILES: Cl.COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1.Cl
• Target: Antioxidant

Bioactivity

• In Vitro:
  BMY 7378 is selective for the alpha 1D-adrenoceptor subtype (pKi: hamster alpha 1b-adrenoceptor 6.2, human alpha 1b-adrenoceptor 7.2; bovine alpha 1c-adrenoceptor 6.1, human alpha 1c-adrenoceptor 6.6; rat alpha 1d-adrenoceptor 8.2, human alpha 1d-adrenoceptor 9.4) and has high affinity (pA2, 8.9) for rat aorta alpha 1-adrenoceptor.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antioxidant