Bleximenib oxalate

SKU: orb2278831

Description

Bleximenib oxalate is a potent and selective menin-MLL inhibitor that disrupts the menin-KMT2A chromatin interaction. It demonstrates antiproliferative effects in acute leukemia cell lines and is a key research tool for studying oncogenic transcription in models of MLL-rearranged leukemia.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2866179-95-3
• MW: 689.82
• Purity: 98.00% (May vary between batches)
• Formula: C₃₄H₅₂FN₇O₇
• SMILES: C(C(O)=O)(O)=O.[C@@H](CCCN(CCOC)C)(C(C)C)N1CC2(CN(CC2)C=3C(OC4=C(C(N(C(C)C)CC)=O)C=C(F)C=C4)=NN=CN3)C1
• Target: Epigenetic Reader Domain,Histone Methyltransferase,FLT,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171034104