Bilobalide

SKU: orb1304993

Description

Bilobalide is a bioactive terpenoid from Ginkgo biloba that modulates cellular responses to hypoxia. It is widely used in neuroscience research, with in vitro and in vivo studies investigating its neuroprotective effects against ischemic injury and oxygen-glucose deprivation.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 33570-04-6
• MW: 326.30
• Purity: 98.81%
• Formula: C₁₅H₁₈O₈
• SMILES: [H][C@]12C[C@@](O)(C(C)(C)C)[C@]34[C@@H](O)C(=O)O[C@@]3([H])OC(=O)[C@]14CC(=O)O2
• Target: Apoptosis,Autophagy,Endogenous Metabolite
• Solubility: DMSO:250.00 mg/mL (766.17 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.00 mg/mL (6.13 mM);Ethanol:60.00 mg/mL (183.88 mM)

Bioactivity

• Target IC50:
  Neuroprotection:3.33 (pIC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

protective, SH-SY5Y, Sesquiterpene, trophic, trilactone, Inhibitor, Ginkgo, EndogenousMetabolite, Endogenous Metabolite, inhibit, NMDA, neurons, (-)-Bilobalide, Apoptosis, Autophagy, biloba, Bilobalide, choline

Compound Identifiers

PubChem CID

73581