Bikinin

SKU: orb1225834

Description

Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases; interferes directly with BIN2 kinase activity, also strongly inhibited the activity of the group I Arabidopsis GSK3 subfamilies, but not the ASKβ, ASKδ, and other Arabidopsis Ser/Thr kinases (AtMPK4, AtMPK6, and AtAURORA1); inhibits the SnRK2.3 kinase activity and its T180 phosphorylation in vivo.

Key Properties

• CAS Number: 188011-69-0
• MW: 273.0834
• Purity: >98% (HPLC)
• Formula: C₉H₉BrN₂O₃
• SMILES: BrC1=CN=C(NC(CCC(O)=O)=O)C=C1
• Target: GSK-3
• Solubility: DMSO: ≥ 42 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Abrasin

Quick Database Links

Gene Symbol

GSK-3