BEX1 (N2) Antibody, Rabbit Polyclonal

SKU: orb387375

Description

Brain-expressed X-linked protein 1 (BEX1) is a signaling adapter molecule involved in p75NTR/NGFR signaling. BEX1 plays a role in cell cycle progression and neuronal differentiation. BEX1 inhibits neuronal differentiation in response to nerve growth factor (NGF). BEX1 may act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states

Research Area

Developmental Biology, Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:1,000-1:3,000 (detect endogenous protein*)
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human BEX1
• Molecular Weight: 15 kDa
• Purity: Antibodies were purified by affinity purification using immunogen
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store at -20 °C. Stable for 6 months from the date of receipt
• Form/Appearance: Supplied in 1 x PBS (pH 7.4), 100 ug/ml rAlbumin, 40% Glycerol, 0.01% NaN3
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Western blot of total cell extracts from A) mouse thymus, B) human Jurkat; using anti-BEX1 (N2) at RT for 2hr

Quick Database Links

UniProt

Q9HBH7