Beta Amyloid Antibody

SKU: orb3169674

Description

Anti-Amyloid Beta Antibody (CNTO 2125) is a recombinant humanized monoclonal antibody targeting human Amyloid Beta (Aβ/Amyloid Beta). Aβ is the core component of amyloid plaques in the Alzheimer's disease (AD) brain, generated from the cleavage of amyloid precursor protein (APP). CNTO 2125 specifically binds to Aβ with high affinity (e.g., EC50 ≈ 9.7 ng/mL), blocking the aggregation of Aβ monomers and promoting the clearance of existing plaques. By targeting the Aβ cascade, this antibody has the potential to protect neurons from Aβ-mediated neurotoxic damage, serving as a critical tool for researching the pathogenesis and immunotherapy of Alzheimer's disease. This antibody features a huIgG1 heavy chain and a hu-kappa light chain.

Research Area

Neuroscience

Key Properties

• Antibody Type: Inhibitor Antibody
• Clonality: Recombinant
• Target: Beta Amyloid
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Beta Amyloid