Beta-Amyloid (1-42) Human peptide

• Catalog Number: orb216483
• Category: Proteins
• Description: Beta-Amyloid (1-42) Human peptide
• Form/Appearance: Lyophilized powder
• Purity: > 95%
• Protein Sequence: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
• MW: 4514.14
• Application notes: Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. The sequence corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide. The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy.
• Source: Synthetic
• CAS Number: 107761-42-2
• Formula: C₂₀₃H₃₁₁N₅₅O₆₀S
• Storage: Shipped at 4°C. Store at -20°C for one year.
• Alternative names: Aβ42
• Note: For research use only
• Expiration Date: 12 months from date of receipt.