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Catalog Number | orb216483 |
---|---|
Category | Proteins |
Description | Beta-Amyloid (1-42) Human peptide |
CAS Number | 107761-42-2 |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
MW | 4514.14 |
Formula | C203H311N55O60S |
Protein Sequence | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
Source | Synthetic |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Alternative names | Aβ42 Read more... |
Note | For research use only |
Application notes | Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. The sequence corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide. The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy. |
Expiration Date | 12 months from date of receipt. |
In vitro, In vivo, WB | |
> 98% | |
4.5 kDa | |
Synthetic |
In vitro, In vivo, WB | |
> 98% | |
4.5 kDa | |
Synthetic |
In vitro, In vivo, WB | |
> 98% | |
4.5 kDa | |
Synthetic |
ELISA, WB | |
Greater than 95% as determined by SDS-PAGE | |
25 kDa | |
E.Coli |
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Really Great Full Length Amyloid-Beta Peptide for Functional Assays. I used this peptide to treat cells with and determine the changes to iron transport. This peptide mimics the conditions of Alzheimer's disease.
- Stephanie Baringer/Penn State College of Medicine
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