Berbamine

SKU: orb1303411

Description

Berbamine is a bioactive bisbenzylisoquinoline alkaloid isolated from Phellodendron amurense, functioning as a calcium channel blocker. It is utilized in research exploring its anti-tumor, immunomodulatory, and cardiovascular effects, with studies conducted in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 478-61-5
• MW: 608.72
• Purity: 99.81% (May vary between batches)
• Formula: C₃₇H₄₀N₂O₆
• SMILES: [H][C@]12Cc3ccc(Oc4cc(C[C@@]5([H])N(C)CCc6cc(OC)c(OC)c(Oc7cc1c(CCN2C)cc7OC)c56)ccc4O)cc3
• Target: Autophagy,CaMK,NF-κB
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:91 mg/mL (149.49 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.42 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, CAMKIIγ, Berbamine, Inhibitor, inhibit, NFκB, NF-kB, NFkB, NF-κB, Nuclear factor-kappaB, Nuclear factor-κB

Compound Identifiers

PubChem CID

275182