Benzyl benzoate

SKU: orb1310342

Description

Benzyl benzoate is a historic scabicide and pediculicide agent effective against Sarcoptes scabiei mites and lice. While its irritant properties limit clinical use, it remains a relevant compound in parasitology research for studying acaricidal mechanisms in vitro and evaluating treatment efficacy in animal models.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 120-51-4
• MW: 212.24
• Purity: 99.75% (May vary between batches)
• Formula: C₁₄H₁₂O₂
• SMILES: O=C(OCc1ccccc1)c1ccccc1
• Target: Antibacterial,Endogenous Metabolite,Antifungal,Parasite,RAAS
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.42 mM);DMSO:260 mg/mL (1225.03 mM)

Bioactivity

• In Vitro:
  Benzyl benzoate possess oestrogenic activity in MCF7 human breast cancer cells in vitro. It is able to increase the growth of oestrogen-dependent MCF7 human breast cancer cells.
• Cell Research:
  Cells are added to the required volume of phenol red-free RPMI 1640 medium containing 5% DCFCS at a concentration of about 0.2 × 105 cells ml−1 and plated in monolayer in 0.5 ml aliquots into 24-well plastic tissue culture dishes (Nunc). After 24 h, the medium is changed to the same medium but containing the required concentration of test compound. Culture medium is changed routinely every 3–4 days. Cell counts are performed by counting released nuclei on a model ZBI Coulter Counter. (Only for Reference)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Benzyl, Benzyl benzoate, Benzyl Benzoate, Benzoic acid benzyl ester, Ascabiol, inhibit, Inhibitor, Novoscabin, Parasite, Scabitox

Compound Identifiers

PubChem CID

2345