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BAY-593

SKU: orb2566874

Description

BAY-593 is a potent and orally bioavailable inhibitor of geranylgeranyltransferase I (GGTase-I). Its anti-tumor activity is achieved through the inhibition of the YAP1/TAZ signaling pathway, as demonstrated in vivo. This small molecule is a valuable research tool for studying Hippo pathway dysregulation in cancer models.

Research Area

Metabolism Research, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2413020-56-9
MW476.53
FormulaC26H31F3N2O3
SMILESO(C)C1=C([C@H]2C3(CCN(C([C@]([C@@](F)(F)F)(OC)C4=CC=CC=C4)=O)CC3)CCNC2)C=CC=C1
TargetTransferase,YAP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

BAY-593 (orb2566874)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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