BAY-545

SKU: orb1298868

Description

BAY-545 is a potent and selective A2B adenosine receptor antagonist with an IC50 of 59 nM. This small molecule inhibitor is a valuable research tool for studying the role of the A2B receptor in various in vitro and in vivo models of inflammation, fibrosis, and cancer.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1699717-32-2
• MW: 433.45
• Purity: 98.05%
• Formula: C₁₈H₂₂F₃N₃O₄S
• SMILES: CCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O
• Target: Adenosine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.23 mM);DMSO:145 mg/mL (334.53 mM)

Bioactivity

• Target IC50:
  A2B receptor:59 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Adenosine Receptor, AdenosineReceptor, A2B, BAY 545, BAY545, BAY-545, inhibit, P1 receptor, Inhibitor

Compound Identifiers

PubChem CID

118016229