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BAY-545

SKU: orb1220139

Description

BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).

Images & Validation

Key Properties

CAS Number1699717-32-2
MW433.45
Purity>98% (HPLC)
FormulaC18H22F3N3O4S
SMILESCCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O
TargetAdenosine Receptor
SolubilityDMSO:145 mg/ml(334.53 mM)

Bioactivity

In Vitro
BAY-545 is selective at A2B adenosine receptor over A1, A2A, and A3 adenosine receptor, with IC50s of 1300 nM (Human A1 adenosine receptor), 820 nM (Human A2A adenosine receptor), 470 nM (Mouse A2A adenosine receptor) and 750 nM (Rat A2A adenosine receptor).

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • BAY-545 [orb1298868]

    98.05% (May vary between batches)

    1699717-32-2

    433.45

    C18H22F3N3O4S

    50 mg, 100 mg, 200 mg, 25 mg, 5 mg, 1 mg, 10 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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200 mg
500 mg
5 mg
$ 460.00
10 mg
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25 mg
$ 1,300.00
50 mg
$ 1,790.00
100 mg
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