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BARD1 (C) Antibody, Rabbit Polyclonal
Catalog Number: orb67159
| Catalog Number | orb67159 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to BARD1.BRCA1-associated RING domain protein 1 (BARD1) is a probable E3 ubiquitin-protein ligase and atumor suppressor. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNAdamage repair, ubiquitination and transcriptional regulation to maintain genomic stability. BARD1plays a central role in the control of the cell cycle in response to DNA damage. It also forms aheterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibitingpre-mRNA 3' cleavage. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | C-terminal region of human BARD1 |
| Dilution range | WB:1:500-1:1000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 87 |
| UniProt ID | Q99728 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-BARD1 antibody,anti-BRCA1associated RING doma Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using BARD1 antibody
