Bad Antibody

• Catalog Number: orb1730520
• Category: Antibodies
• Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: FC, ICC, IHC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Bad
• Dilution range: IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200; RCM: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 18 kDa; Observed MW: 23 kDa
• Entrez: 572
• UniProt ID: Q92934
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Alternative names: BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death;
• Note: For research use only
• Expiration Date: 12 months from date of receipt.