Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

B-Raf IN 9

SKU: orb1688103

Description

B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor with an enzymatic IC50 of 24.79 nM. It demonstrates anti-proliferative activity by inducing G2/M cell cycle arrest and apoptosis in PC-3 prostate cancer cells, with a cellular IC50 of 7.83 µM, supporting its use in oncology research for studying kinase signaling pathways.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2477725-18-9
MW400.5
FormulaC23H20N4OS
SMILESO=C1N(N=C(CC1)C2=CC=C(NC(NC3=CC=CC=C3)=S)C=C2)C4=CC=CC=C4
TargetApoptosis,Others,Raf

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Dabrafenib Mesylate [orb1298903]

    99.82% (May vary between batches)

    1195768-06-9

    615.67

    C24H24F3N5O5S3

    5 mg, 10 mg, 50 mg, 100 mg, 500 mg, 25 mg, 1 ml x 10 mM (in DMSO)
  • PROTAC B-Raf degrader 1 [orb1708803]

    2364367-27-9

    763.77

    C36H37N5O12S

    50 mg, 100 mg, 5 mg, 10 mg
  • CCT196969 [orb1226891]

    >98% (HPLC)

    1163719-56-9

    513.5229

    C27H24FN7O3

    5 mg, 25 mg, 50 mg, 10 mg, 100 mg, 200 mg, 500 mg, 1 g, 2 mg
  • Dabrafenib Mesylate [orb1220071]

    >98% (HPLC)

    1195768-06-9

    615.67

    C24H24F3N5O5S3

    5 mg, 100 mg, 10 mg, 25 mg, 50 mg, 500 mg, 1 g
  • Trametinib [orb1223790]

    >98% (HPLC)

    871700-17-3

    615.3948

    C26H23FIN5O4

    5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information