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B-Raf IN 6

SKU: orb1686182

Description

B-Raf IN 6 is a potent and selective B-Raf kinase inhibitor (IC50 = 1.7 nM) with favorable drug-like properties, including no PXR binding and metabolic stability. It is a valuable research tool for investigating B-Raf-driven signaling pathways in cancer, applicable in both in vitro cellular assays and in vivo preclinical models.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2648698-34-2
MW546.59
FormulaC24H21F3N6O2S2
SMILESFC1=C(C2=C(SC(=N2)C3CCCCN3)C4=NC(N)=NC=C4)C=CC=C1NS(=O)(=O)C5=C(F)C=CC(F)=C5
TargetOthers,Raf

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information