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B-Raf IN 2

SKU: orb1690702

Description

B-Raf IN 2 (compound Ia) is a potent and selective BRAF kinase inhibitor. It is a valuable research tool for investigating oncogenic BRAF signaling in both cellular assays and in vivo models, supporting cancer drug discovery and mechanistic studies.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2649372-20-1
MW461.44
Purity98.86% (May vary between batches)
FormulaC20H17F2N5O4S
SMILESCn1cnc2ccc(Oc3c(F)ccc(NS(=O)(=O)N4CC[C@@H](F)C4)c3C#N)cc2c1=O
TargetRaf
Solubility10% DMSO+90% Corn Oil:3.3 mg/mL (7.15 mM);DMSO:90 mg/mL (195.04 mM)

Bioactivity

In Vitro
B-Raf IN 2 demonstrates significantly reduced paradoxical activation of the MAPK signaling pathway while maintaining high efficacy .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

B Raf IN 2, BRaf IN 2, B-Raf IN 2, B-Raf

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
10 mg
$ 240.00
25 mg
$ 400.00
50 mg
$ 540.00
100 mg
$ 740.00
DispatchUsually dispatched within 5-10 working days
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