Azido-PEG10-alcohol

SKU: orb1217546

Description

Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	877239-09-3
MW	483.55
Purity	>98% (HPLC)
Formula	C₂₀H₄₁N₃O₁₀
SMILES	OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Target	PROTAC
Solubility	DMSO:10 mM

Bioactivity

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In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

PROTAC

Protocol Information

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Purity:	≥98% (May vary between batches)
CAS Number:	877239-09-3
MW:	483.55
Formula:	C₂₀H₄₁N₃O₁₀