Azasetron hydrochloride

SKU: orb1308305

Description

Azasetron hydrochloride (Y-25130 HCl) is a selective 5-HT3 receptor antagonist used in research as an anti-emetic. It is applied in studies investigating chemotherapy-induced nausea and vomiting, utilizing both in vitro receptor binding assays and in vivo animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 123040-16-4
• MW: 386.27
• Purity: >99.99% (May vary between batches)
• Formula: C₁₇H₂₀ClN₃O₃·HCl
• SMILES: Cl.CN1C(=O)COc2c1cc(Cl)cc2C(=O)NC1CN2CCC1CC2
• Target: 5-HT Receptor
• Solubility: DMSO:Insoluble;H2O:10 mM

Bioactivity

• Target IC50:
  5-HT3:0.33 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Azasetron, Azasetron HCl, Azasetron hydrochloride, Azasetron Hydrochloride, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, 5-HT Receptor, 5-HT3, Chemotherapy, CINV, inhibit, nausea, Inhibitor, Serotonin Receptor, Y 25130, Y 25130 Hydrochloride, Y25130, Y-25130, Y-25130 HCl, Y25130 Hydrochloride, Y-25130 hydrochloride, Y-25130 Hydrochloride, vomiting

Compound Identifiers

PubChem CID

115000