AZ5576

SKU: orb1689803

Description

AZ5576 is a potent and selective CDK9 inhibitor used in hematological malignancy research. It has been employed in both in vitro and in vivo studies to investigate mechanisms of transcriptional regulation and cancer cell survival.

Research Area

Cell Biology

Key Properties

• CAS Number: 2751721-40-9
• MW: 385.43
• Purity: >99.99% (May vary between batches)
• Formula: C₂₁H₂₄FN₃O₃
• SMILES: COc1cc(F)ccc1-c1ccnc(NC(=O)[C@H]2CCC[C@H](C2)NC(C)=O)c1
• Target: CDK,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.19 mM);DMSO:45 mg/mL (116.75 mM)

Bioactivity

• Target IC50:
  CDK9:<5 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AZ5576, AZ-5576, AZ 5576, CDK9

Compound Identifiers

PubChem CID

53373586