AZ5576 racemate

SKU: orb1738527

Description

AZ5576 racemate is a potent, selective, and orally bioavailable CDK9 inhibitor with an enzyme IC50 <5 nM. It reduces RNAPII phosphorylation and Mcl1 expression, inducing apoptosis in MLL-fusion AML models like MV4;11 cells, supporting its use in oncology research for studying transcriptional dependencies in vitro.

Research Area

Cell Biology

Key Properties

• CAS Number: 1333468-05-5
• MW: 385.43
• Formula: C₂₁H₂₄FN₃O₃
• SMILES: O(C)C1=C(C=2C=C(NC(=O)[C@@H]3C[C@H](NC(C)=O)CCC3)N=CC2)C=CC(F)=C1
• Target: Bcl-2 Family,Others,c-Myc,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53373586