Avexitide

SKU: orb1296372

Description

Avexitide, also known as Exendin (9-39), is a potent and selective competitive antagonist of the glucagon-like peptide-1 (GLP-1) receptor. It is widely used in metabolic research to investigate GLP-1 signaling in both in vitro cellular assays and in vivo models of glucose homeostasis and insulin secretion.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Glucagon Receptor
• CAS Number: 133514-43-9
• MW: 3369.76
• Purity: 99.65% (May vary between batches)
• Formula: C₁₄₉H₂₃₄N₄₀O₄₇S
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Exendin, Exendin (9-39), Exendin-3, Exendin-3 Amide, Exendin-3 (9-39) amide, Glucagon Receptor, GlucagonReceptor, GLP-1, GCGR, Inhibitor, Avexitide

Compound Identifiers

PubChem CID

16198321