Autocamtide-2-related inhibitory peptide

SKU: orb1296330

Description

Autocamtide-2-related inhibitory peptide (AIP) is a highly specific and potent CaMKII inhibitor with an IC50 of 40 nM. It is widely used in neuroscience and cardiovascular research to probe CaMKII's role in synaptic plasticity, arrhythmias, and ischemic injury in both cellular and animal models.

Research Area

Cell Biology, Neuroscience

Key Properties

• Target: CaMK,Autophagy
• CAS Number: 167114-91-2
• MW: 1497.74
• Purity: >99.99% (May vary between batches)
• Formula: C₆₄H₁₁₆N₂₂O₁₉
• SMILES: [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CCCCN)=O)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)CC(O)=O)=O)C(C)C)=O)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, Autocamtide 2 related inhibitory peptide, Autocamtide2related inhibitory peptide, Autocamtide-2-related inhibitory peptide, Calmodulin-dependent protein kinases, Calmodulin-dependent kinases, CaMK, CaMKII, inhibit, Inhibitor

Compound Identifiers

PubChem CID

25031982