Autocamtide-2-related inhibitory peptide TFA salt

SKU: orb1296706

Description

The TFA salt of Autocamtide-2-related inhibitory peptide is a potent and selective CaMKII inhibitor with an IC50 of 40 nM. It is widely used in neuroscience and cardiovascular research to study CaMKII's role in synaptic plasticity, cardiac function, and memory in both cellular and animal models.

Research Area

Immunology & Inflammation; Pharmacology & Drug Discovery, Neuroscience

Key Properties

• Target: CaMK
• MW: 1611.77
• Purity: >99.99% (May vary between batches)
• Formula: C₆₆H₁₁₇F₃N₂₂O₂₁
• SMILES: C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)N.C(=O)(C(F)(F)F)O

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autocamtide-2-related inhibitory peptide, Autocamtide-2-related inhibitory peptide (TFA), CaMKII, CaM kinase II inhibitor TFA, CaM kinase II inhibitor TFA salt

Compound Identifiers

PubChem CID

126456179