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AURKA against 1

SKU: orb2663644

Description

Compound Ac13 (AURKA inhibitor 1) is a potent and selective Aurora kinase A (AURKA) inhibitor with sub-nanomolar IC50. It suppresses tumor cell proliferation by targeting the acetylation of endogenous lysine K162, a modification reversibly regulated by SIRT3 in cellular models like HCT116. This inhibitor is a valuable tool for studying AURKA signaling in cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Images & Validation

Key Properties

MW545.61
FormulaC28H32FN9O2
TargetAurora Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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