AURKA-IN-4

SKU: orb3172995

Description

AURKA-IN-4 is a novel capsaicin analog that acts as an Aurora kinase A (AURKA) inhibitor. By specifically targeting AURKA in mitochondria, AURKA-IN-4 inhibits AURKA-dependent mitophagy, thereby eliminating the organelle. AURKA-IN-4 exhibits antiproliferative effects against various tumor cells and holds potential value for application in anticancer therapies that target cell cycle regulation.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 89575-11-1
• MW: 223.27
• Purity: 99.98% (May vary between batches)
• Formula: C₁₂H₁₇NO₃
• SMILES: O=C(NCC1=CC=C(O)C(OC)=C1)CCC
• Target: Molecular Glues,Mitochondrial Metabolism,Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Molecular Glues,Mitochondrial Metabolism,Aurora Kinase