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ATX inhibitor 27

SKU: orb3027730

Description

ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC). By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2023027-81-6
MW491.97
FormulaC26H26ClN5O3
SMILESN#CC1=CC=C(C=C1Cl)CN(C(=O)CN2C=NC=3C=CC(=CC3C2=O)C4CCN(C(=O)C)CC4)C
TargetLPL Receptor,PDE

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information