ATX inhibitor 11

SKU: orb1685899

Description

ATX inhibitor 11 is a potent, nanomolar-range inhibitor of autotaxin (IC50: 2.7 nM). It has demonstrated efficacy in reducing fibrosis severity and α-SMA deposition in a murine model, making it a valuable research tool for studying lung fibrosis and related fibrotic diseases in both in vitro and in vivo settings.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2485779-27-7
• MW: 585.65
• Purity: 99.96% (May vary between batches)
• Formula: C₃₂H₃₅N₅O₆
• SMILES: O=C(OCC1=CC=C2OCOC2=C1)NC3=C(N=C4C(=CC(=CN43)C=5C=CC(=CC5)C(=O)N6CCN(CCO)CC6)C)CC
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

153533008