Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Atopaxar

SKU: orb1705936

Description

Atopaxar (E5555) is a reversible protease-activated receptor-1 (PAR-1) antagonist that inhibits thrombin-mediated platelet aggregation. It has been studied in preclinical and clinical research for the potential management of acute coronary syndrome and coronary artery disease.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number751475-53-3
MW527.63
Purity98.50% (May vary between batches)
FormulaC29H38FN3O5
SMILESCCOc1cc2CN(CC(=O)c3cc(N4CCOCC4)c(OC)c(c3)C(C)(C)C)C(=N)c2c(F)c1OCC
TargetJAK,Protease-activated Receptor,Apoptosis
SolubilityDMSO:30 mg/mL (56.86 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.79 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, platelets, PAR-1, ER-172594-00, Inhibitor, atherothrombotic, Atopaxar, E 5555, E5555, E-5555, receptor-1, receptor, signaling, Protease Activated Receptor (PAR), protease-activated, Protease-Activated Receptor (PAR), Proteaseactivated Receptor, ProteaseactivatedReceptor, thrombin, Thrombin receptors

Similar Products

  • Atopaxar hydrochloride [orb1705931]

    474544-83-7

    564.1

    C29H39ClFN3O5

    50 mg, 100 mg, 25 mg
  • Atopaxar Hydrobromide [orb1705932]

    >99.99% (May vary between batches)

    474550-69-1

    608.54

    C29H39BrFN3O5

    5 mg, 10 mg, 1 mg, 25 mg
  • Atopaxar Hydrobromide [orb1224895]

    >98% (HPLC)

    50-69-1

    608.54

    C5H10O5

    100 mg, 200 mg, 500 mg, 1 g
  • Atopaxar [orb1224074]

    >98% (HPLC)

    751475-53-3

    527.6374

    C29H38FN3O5

    5 mg, 25 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
  • Atopaxar hydrobromide [orb1225003]

    >98% (HPLC)

    474550-69-1

    608.54

    C29H38FN3O5.HBr

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 200.00
10 mg
$ 300.00
25 mg
$ 510.00
50 mg
$ 730.00
100 mg
$ 1,010.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry