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Atopaxar Hydrobromide

SKU: orb1705932

Description

Atopaxar is a reversible antagonist of the PAR-1 thrombin receptor, inhibiting platelet activation pathways. It has been studied in preclinical and clinical research contexts for the potential management of coronary artery disease and acute coronary syndromes.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number474550-69-1
MW608.54
Purity>99.99% (May vary between batches)
FormulaC29H39BrFN3O5
SMILESBr.CCOc1cc2CN(CC(=O)c3cc(N4CCOCC4)c(OC)c(c3)C(C)(C)C)C(=N)c2c(F)c1OCC
TargetProtease-activated Receptor,JAK,Apoptosis
SolubilityDMSO:10 mM

Bioactivity

Target IC50
PAR1:5.1 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

E5555, E-5555, E 5555, atherothrombotic, Atopaxar, Atopaxar Hydrobromide, PAR-1, platelets, inhibit, Inhibitor, ER 172594-06, Thrombin receptors, thrombin, receptor, receptor-1, signaling, Protease Activated Receptor (PAR), ProteaseactivatedReceptor, protease-activated, Proteaseactivated Receptor

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 300.00
2 mg
$ 420.00
5 mg
$ 680.00
10 mg
$ 930.00
25 mg
$ 1,410.00
50 mg
$ 1,820.00
DispatchUsually dispatched within 3-5 working days
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