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ATIC-IN-1

ATIC-IN-1

Catalog Number: orb1941820

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Product Properties
Catalog Numberorb1941820
CategorySmall Molecules
DescriptionATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates.
TargetOthers
MW463.53
CAS Number1402453-15-9
FormulaC21H33N7O5
SMILES[C@@H](CC1=CC=C(N(=O)=O)C=C1)(NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C(N(CC)CC)=O
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
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