Atg16L1 Rabbit mAb [KD Validated] Antibody

SKU: orb1951033

Description

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Images & Validation

• Tested Applications: IHC, WB
• Dilution range: WB 1:500~1:2000 IHC 1:50~1:200
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Atg16L1
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Disclaimer: For research use only

Alternative Names

APG16 like 1; APG16L; APG16L beta; ATG16A; ATG16L; Atg16l1; IBD10; WD repeat domain 30; WDR30;

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Atg16L1 expression in HeLa cell lysate.

Quick Database Links

UniProt

Q676U5