ASyO5 Mouse Monoclonal Antibody (Biotin)

SKU: orb303321

Description

Mouse monoclonal antibody to ASyO5-biotinylated | Mouse anti-human alpha-synuclein | oligomer-specific

Research Area

Neuroscience

Images & Validation

• Tested Applications: ELISA
• Dilution Range: ELISA: 2-4 μg/ml
• Reactivity: Human
• Application Notes:
  Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed.

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Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Immunogen: synthetic peptide derived from human alpha-synuclein Gly111-Tyr125
• Molecular Weight: 14 kDa
• Purification: Immunogen affinity purified serum in PBS pH 7.4.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Lyophilized
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only