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AS601245

SKU: orb1305636

Description

AS601245 is a potent and selective c-Jun N-terminal kinase (JNK) inhibitor. It exhibits neuroprotective effects and is widely used in research to study JNK signaling pathways in cellular models of apoptosis, inflammation, and in animal models of neurological disorders.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number345987-15-7
MW372.45
Purity99.02% (May vary between batches)
FormulaC20H16N6S
SMILESN#CC(c1nc2ccccc2s1)c1ccnc(NCCc2cccnc2)n1
TargetJNK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.68 mM);DMSO:50 mg/mL (134.25 mM)

Bioactivity

Target IC50
JNK3 (human):70 nM|JNK1 (human):150nM|JNK2 (human):220nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-Inflammatory, AS601245, AS-601245, AS 601245, cancer, colon, cells, Inhibitor, JNK, inhibit, neuroprotective, hJNK1, hJNK2, hJNK3, TNF-α, release

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 150.00
10 mg
$ 220.00
25 mg
$ 330.00
50 mg
$ 470.00
100 mg
$ 680.00
DispatchUsually dispatched within 5-10 working days
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