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ARRY380

SKU: orb1223587

Description

ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.

Images & Validation

Key Properties

CAS Number937265-83-3
MW569.63
Purity>98% (HPLC)
FormulaC29H27N7O4S
SMILESCC1=C(OC2=CC3=NC=NN3C=C2)C=CC(NC2=NC=NC3=C2C=C(C=C3)C2=CC=C(CNCCS(C)(=O)=O)O2)=C1
TargetEGFR
SolubilityDMSO: > 10mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ARRY-380 analog | ONT380 analog | ONT 380 analog | ONT-380 analog

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Protocol Information

ARRY380 (orb1223587)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 120.00
5 mg
$ 180.00
10 mg
$ 270.00
25 mg
$ 440.00
50 mg
$ 630.00
100 mg
$ 910.00