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Catalog Number | orb1308639 |
---|---|
Category | Small Molecules |
Description | ARP-100 |
CAS Number | [704888-90-4] |
Purity | 98.24% |
MW | 364.42 |
SMILES | CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |
Formula | C17H20N2O5S |
Biological Activity | ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM) and MMP-9 (0.2 μM)[1][2]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |