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ARP-100

ARP-100

Catalog Number: orb1308639

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$ 140.00
Catalog Numberorb1308639
CategorySmall Molecules
DescriptionARP-100
CAS Number[704888-90-4]
Purity98.24%
MW364.42
SMILESCC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
FormulaC17H20N2O5S
Biological ActivityARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM) and MMP-9 (0.2 μM)[1][2].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.