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ARP-100

SKU: orb1217712

Description

ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).

Images & Validation

Key Properties

CAS Number704888-90-4
MW364.42
Purity>98% (HPLC)
FormulaC17H20N2O5S
SMILESCC(C)ON(CC(NO)=O)S(c(cc1)ccc1-c1ccccc1)(=O)=O
TargetMMP
SolubilityDMSO:96 mg/mL (263.43 mM; Need ultrasonic)

Bioactivity

In Vitro
ARP-100 (50 nM) shows a significant reduction in the total number of invasive elongations.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MMP-2 Inhibitor III | ARP100

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  • ARP-100 [orb1308639]

    98.34% (May vary between batches)

    704888-90-4

    364.42

    C17H20N2O5S

    10 mg, 25 mg, 50 mg, 100 mg, 5 mg, 1 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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200 mg
500 mg
5 mg
$ 120.00
10 mg
$ 170.00
25 mg
$ 320.00
50 mg
$ 590.00
100 mg
$ 930.00