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ARN-2966

SKU: orb1227139

Description

ARN-2966 is a potent, BBB penetrant post-transcriptional modulator of APP expression in transfected CHO cells that produce amyloid precursor protein (APP); reduces expression of APP with resultant lower production of Aβ; improves the memory and reduces Aβ in AD transgenic mice; orally active.

Images & Validation

Key Properties

CAS Number102212-26-0
MW200.2365
Purity>98% (HPLC)
FormulaC12H12N2O
SMILESC1=CC=C(C(=C1)NCC2=CC=CC=N2)O
TargetAmyloids
SolubilityDMSO: ≥ 43.4 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ARN2966 | ARN 2966

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    102212-26-0

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    5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 500 mg, 1 ml x 10 mM (in DMSO), 1 mg
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Protocol Information

ARN-2966 (orb1227139)

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% DMSO +
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%

Available Sizes

Select a size below

5 mg
$ 130.00
10 mg
$ 190.00
25 mg
$ 350.00
50 mg
$ 540.00
100 mg
$ 780.00
500 mg
$ 1,660.00