Arbidol

SKU: orb1685431

Description

Arbidol (Umifenovir) is a broad-spectrum antiviral fusion inhibitor targeting the SARS-CoV-2 spike protein. It exhibits activity against various coronaviruses in vitro and has demonstrated anti-inflammatory and antioxidant properties in research models for studying viral pathogenesis.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 131707-25-0
• MW: 477.42
• Purity: 99.57% (May vary between batches)
• Formula: C₂₂H₂₅BrN₂O₃S
• SMILES: O=C(OCC)C=1C=2C(=CC(Br)=C(O)C2CN(C)C)N(C1CSC=3C=CC=CC3)C
• Target: Influenza Virus,Antiviral,SARS-CoV

Bioactivity

• In Vivo:
  Arbidol (25 and 45 mg/ml; p.o.; 6–8 weeks old BALB/c mice) shows a survival benefit to mice suffering from influenza infection. Increased the survival rate, inhibited the decrease of body weight at 45 mg/mL, and inhibited the increase of mice lung index at 25 mg/mL and 45 mg/mL compared to the virus group.
• In Vitro:
  Arbidol exhibits potent antiviral activity against a wide range of viruses, including influenza viruses A, B, and C, respiratory syncytial virus, SARS-CoV, adenovirus, parainfluenza type 5, poliovirus 1, rhinovirus 14, coxsackievirus B5, hantaan virus, Chikungunya virus, HBV, and HCV.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antiviral, Arbidol, SARS-CoV-2, SARSCoV, Umifenovir

Compound Identifiers

PubChem CID

131411