Apramycin sulfate

SKU: orb1224321

Description

Apramycin sulfate is an aminoglycoside antibiotic mproduced by a strain of Streptomyces tenebrarius, used in veterinary practice.

Key Properties

• CAS Number: 65710-07-8
• MW: 637.66
• Purity: >98% (HPLC)
• Formula: C₂₁H₄₃N₅O₁₅S
• SMILES: O[C@H]1[C@@H](O[C@@H]2[C@@H](NC)[C@@H](O)[C@]3([H])[C@@](C[C@@H](N)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](N)C[C@@H]4N)O3)([H])O2)O[C@H](CO)[C@@H](N)[C@@H]1O.O=S(O)(O)=O
• Target: Antibacterial
• Solubility: Water: 100 mg/mL (156.82 mM)

Bioactivity

• In Vivo:
  Animal model: M. tuberculosis low-dose aerosol infection model of IFN-γ knockout mice. Dosage: 200 mg/kg/d. Administration: Subcutaneous injection (s. c.) for 9 d. Result: Showed a 2.4-log10 CFU reduction and better antituberculous activity compared to Amikacin (1.8-log10 reduction).

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nebramycin II

Quick Database Links

Gene Symbol

Antibacterial