UBE3A Rabbit Monoclonal Antibody

SKU: orb547390

Description

UBE3A Rabbit Monoclonal Antibody

Research Area

Cell Biology, Epigenetics & Chromatin, Neuroscience, Signal Transduction

Images & Validation

• Tested Applications: WB
• Dilution Range: WB 1:500-2000
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone No.: ADBA-21
• Immunogen: A synthesized peptide derived from human UBE3A E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.
• Target: Ubiquitin-protein ligase E3A
• Molecular Weight: 47 kDa
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
• Concentration: 0.5mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Interferon regulatory factor 1; IRF-1; IRF1

WB analysis of UBE3A expression in K562 Cell using anti-UBE3A antibody.

Quick Database Links

Gene Symbol

Ubiquitin-protein ligase E3A

UniProt

Q05086