Anti-TROP2 Reference Antibody

• Catalog Number: orb1805430
• Category: Antibodies
• Description: Anti-TROP2 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.06 kDa.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 146.06 kDa
• Target: TROP2
• Endotoxins: < 1 EU/mg
• Storage: -80°C
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-TROP2 Reference Antibody (Sacituzumab-MMAE) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

The purity of Anti-TROP2 Reference Antibody (Sacituzumab-MMAE)is more than 95% ;determined by SEC-HPLC.

Sacituzumab-ADC inhibited the tumor growth of MDA-MB-231 on NSG mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 80.0% at 5 mpk at D37.