TRF2 Rabbit Monoclonal Antibody

SKU: orb547420

Description

TRF2 Rabbit Monoclonal Antibody

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

• Tested Applications: ICC, IF, IHC, WB
• Dilution Range: WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone No.: BCHQDX42
• Immunogen: A synthesized peptide derived from human TRF2 Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo.
• Target: Telomeric repeat-binding factor 2
• Molecular Weight: 42 kDa
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
• Concentration: 0.5mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; 2.7.11.1; DNPK1; p460; PRKDC; HYRC, HYRC1

WB analysis of TERF2 expression in Jurkat Cell using anti-TERF2 antibody.

Quick Database Links

Gene Symbol

Telomeric repeat-binding factor 2

UniProt

Q15554