SMAD2/3 (Phospho-T8) Rabbit Polyclonal Antibody

SKU: orb224172

Description

The SMAD2/3 (Phospho-T8) Antibody is suitable for IHC, WB. It is a Polyclonal, Unconjugated antibody which raised against KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T8 of human SMAD2/3 protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography.

Research Area

Cancer Biology

Images & Validation

• Tested Applications: IHC, WB
• Dilution Range: WB: 1:500-1:1000
• Reactivity: Bovine, Gallus, Human, Mouse, Rat, Zebrafish

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T8 of human SMAD2/3 protein. The exact sequence is proprietary.
• Target: SMAD2; SMAD3
• Purification: The antibody was purified by immunogen affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SMAD2; MADH2; MADR2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2; SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Quick Database Links

Gene Symbol

SMAD2; SMAD3

UniProt

Q8BUN5, Q62432, O70436, P84022, Q15796, P84025

NCBI Gene ID

25631, 29357, 4087, 4088, 17126, 17127

Bortolozzi, Roberta et al. Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All) Biochem Pharmacol, 153, 230-241 (2018)

PubMed: 29408328