SIRT1 Rabbit Monoclonal Antibody

SKU: orb546983

Description

Anti-SIRT1 Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Research Area

Cancer Biology, Cell Biology, Disease Biomarkers, Epigenetics & Chromatin, Metabolism Research, Microbiology

Images & Validation

• Tested Applications: ICC, IF, IHC, IP, WB
• Dilution Range: WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:30
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone No.: GG-19
• Immunogen: A synthesized peptide derived from human SIRT1 This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
• Target: NAD-dependent protein deacetylase sirtuin-1
• Molecular Weight: 120 kDa
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
• Concentration: 0.5mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

WB analysis of SIRT1 using anti-SIRT1 antibody on Jurkat Cell.

Immunofluorescent analysis of HeLa cells, using SIRT1 Antibody.

IHC analysis of SIRT1 using anti-SIRT1 antibody on human kidney.SIRT1 was detected in paraffin-embedded section.

Quick Database Links

Gene Symbol

NAD-dependent protein deacetylase sirtuin-1

UniProt

Q96EB6