RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody

• Catalog Number: orb547658
• Category: Antibodies
• Description: RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody
• Clonality: Monoclonal
• Species/Host: Rabbit
• Isotype: Rabbit IgG
• Conjugation: Unconjugated
• Reactivity: Human, Mouse, Rat
• Form/Appearance: Liquid
• Concentration: 0.5mg/ml
• Purification: Affinity-chromatography
• Immunogen: A synthesized peptide derived from human RING2 / RING1B / RNF2 E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
• UniProt ID: Q99496
• MW: 17 kDa
• Tested applications: FC, ICC, IF, IHC, WB
• Application notes: WB 1:500-2000IHC 1:50-200ICC/IF 1:50-200FC 1:50. Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Antibody Type: Primary Antibody
• Clone Number: AEDC-18
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Vinculin; Metavinculin; MV; VCL
• Note: For research use only

Western blot analysis of RNF2 expression in HeLa cell lysate using anti-RNF2 antibody.