Anti-OX40L [R4930 (Oxelumab)]

• Catalog Number: orb348867
• Category: Antibodies
• Description: Human monoclonal antibody to OX40L
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: R4930 (Oxelumab)
• Tested applications: Blocking, FC
• Reactivity: Human
• Isotype: IgG1
• Immunogen: Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: OX40L
• UniProt ID: P23510
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: CD252; TNFSF4; tumor necrosis factor (TNF) superfa
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Flow-cytometry using the anti-OX40L antibody R4930 (Oxelumab) Human peripheral blood leukocytes were fixed using 2% PFA, permeabilised using 0.5% Triton and stained with unimmunized rabbit IgG antibody (MOPC-21; isotype control, black line) or the rabbit IgG-chimeric version of R4930 (orb378214, blue line) at a dilution of 1:100 for 1h at RT. After washing, bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.